Welcome to the ACTS Learning Library, the centralized location for all ACTS educational offerings, including partner webinars and past Translational Science recordings.
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Past Translational Science Recordings
What: Translational Science 2020 - Virtual Sessions 1
When: April 15, 2020
- Welcome | Fred Meyers, MD, MACP
- Introduction of CR Forum Top 10 | Anne B. Curtis, MD MACP, FACC, FHRS, FAHA
- Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy, Kenneth Mahaffey, MD
- Hematopoietic Stem Cell Transplantation for Frequently Relapsing Multiple Sclerosis, Richard Burt, MD
- Skin-like Devices for Wireless Monitoring of Vital Signs in Neonatal Intensive Care, John Rogers, MD
- CR Forum Q&A | Moderated by Harry Selker, MD
- Panel Discussion: COVID-19: How Researchers Can Turn Crisis into Opportunity | Moderator: Robert Kimberly, MD
- Panelists: Simeon Abiola, PhD; Mark Burge, MD; Rajpreet Chahal, PhD; Martha Gay, PhD; Chris Lindsell, PhD; Fred Meyers, MD, MACP; Zachary Rivers, PharmD; Kathryn Sandberg, PhD; Liane Schneller, PhD, MS; Cherry Wongtrakool, MD
- Closing | Fred Meyers, MD, MACP
What: Translational Science 2020 - Virtual Sessions 2
When: April 16, 2020
- Welcome | Chris Lindsell, PhD
- Fireside Chat with Amy Abernethy, MD, PhD | Interview by Scott Steele, PhD
- ACTS Abstract Presentations
- Unique Vaginal Microbiome Populations and Microbial Gene Content Among Women Who Naturally Control HIV Progression, Katherine Michel
- Nilotinib Alters MicroRNAs that Regulate Specific Autophagy and Ubiquitination Genes in the Cerebrospinal Fluid of Parkinson's Patients, Alan Fowler
- Deep-primed IL-15 Superagonist Improves Antiviral Efficacy of HIV-specific CD8+ T-Cells in Humanized Mouse Model, Chase McCann
- Moderated Q&A | Moderated by Kathryn Sandberg, PhD
- Translational Science’s Finest Hour – Use the Moment Well, David Skorton, MD
- ACTS Abstract Presentations | Moderated by Kathryn Sandberg, PhD
- Hollow, Degradable poly(N-Isopropylacrylamide) Derived Nanoparticles for the Delivery of Anti-Inflammatory Peptides for the Treatment and Prevention of Post-Traumatic Osteoarthritis, Marcus Deloney
- Matrix-bound Nanovesicles as a Novel Therapeutic Option for the Treatment of Rheumatoid Arhtritis, Raphael Crum
- Heart Transplant Candidates Listed at Low First-Offer Organ Acceptance Rate Centers are More Likely to Die Waiting, Ashley Choi
- Closing | Chris Lindsell, PhD
Translational Science 2019
Education and Career Development Bundle
This bundle includes the following sessions, recorded at Translational Science 2019:
- Novel Approaches to Successful Grant Writing (Transitions)
- Mentorship is Vital for Success During Mid-Career
- Scientific Communication Skills for Pre-Doctoral Trainees
- How to Write a Successful F Award
Data in Science Bundle
This bundle includes the following sessions, recorded at Translational Science 2019:
- Conducting Full-Spectrum Translational Research: Big Data Meets Embedded Mechanistic Studies
- Predictive Modeling and AI in Healthcare: What to Do with Garbage
Novel Approaches to Successful Grant Writing (Transitions)
Recording: Introduces a novel way for teaching and learning the skill of writing NIH-style research proposals, as well as key elements of transitioning from K to R funding.
Speaker: Richard McGee, Jr, PhD, Northwestern University
Mentorship is Vital for Success During Mid-Career
Recording: Early & Mid-career faculty, post-tenure faculty, and faculty in leadership positions can all benefit from a mentoring relationship. Mentoring can shape the plan for the mid-career transition and mid career related priorities. A supportive & collaborative network for faculty at mid-career is just as important, if not more so, than in early career faculty development. Mid-Career faculty & Scientists are often left to consider various questions of meaning/identity of career, navigating a plateau when professional goals are less clear, leadership opportunities within the organization and nationally, and legacy of career.
Speakers: Frederick J. Meyers, MACP, University of California, Davis and Sharon Rounds, MD, Brown University
Scientific Communication Skills for Pre-Doctoral Trainees
Recording: A key factor for success in science is the ability to communicate clearly and succinctly utilizing language appropriate to the audience. NIH has defined communication competency as the ability to “communicate clinical and translational research findings to different groups of individuals, including colleagues, students, the lay public and the media.” A scientist’s career will “soar” or “sink” based on their ability to communicate their science through oral and written communication channels. This workshop, recorded at Translational Science 2019, focuses on oral presentation skills and through brief presentations and utilization of tools provides critical information to:
- Understand the professional VALUE of oral presentations
- Identify WHO your audience is
- Identify WHAT is the relevant information that they need to hear
- Identify WHY this audience need to know this
- Give an effective presentation
Speakers: Stephen C. Ekker, Mayo Clinic; Becca Gas, Mayo Clinic; Anthony Windebank, Mayo Clinic
Moderator: Karen Weavers, Mayo Clinic
How to Write a Successful F Award
Recording: Covers how to put together a successful application for a NIH F-award to support their pre-doctoral research as a PhD or MD-PhD student or as a postdoctoral fellow.
Speakers: Linda M. McManus, University of Texas Health Sciences Center, San Antonio and Stephen C. Ekker, Mayo Clinic
Conducting Full-Spectrum Translational Research: Big Data Meets Embedded Mechanistic Studies
Recording: The Rockefeller University Center for Clinical and Translational Science (RU-CCTS) Clinical Scholars (KL2) Program provides an optimal environment for translational investigator trainees to develop team science and leadership skills. Clinical scholars and early-career physician–scientists are encouraged to include T3–T4 translational aims to align with their T0-T1 experiments, by designing and performing a human subjects protocol under the supervision of a senior investigator mentor and a team of content expert educators.
This case presentation illustrates how an early-career physician-scientist posing basic science questions about metabolic outcomes of bariatric surgery engaged with a practice-based research network (PBRN) and clinicians at a Federally Qualified Health Center (FQHC), to jointly generate a set of exploratory hypotheses of interest to both basic scientists and practicing clinicians, and to examine these hypotheses in a de-identified electronic health records (EHR) data study (n=236) funded by a CTSA pilot grant. This initial single-site study was subsequently extended as part of a national “Big Data” study (n=65,093) conducted with PCORnet, a federated network of clinical data research networks (CDRNs). The national project secured external funding (PCORI), engaged community partners as co-investigators and coauthors, and disseminated results through presentations and publications (Annals of Internal Medicine 2018).
Goals of this “full-spectrum” translational research are to: (1) identify which patients will respond to bariatric surgery with significant and sustained weight loss and improvement in glucose homeostasis, and (2) generate mechanistic hypothesis to be tested on the bench with mouse models, and in a research hospital with noninvasive human protocols (imaging studies, biological specimens) to elucidate how bariatric surgery leads to weight loss and improvement in glucose homeostasis. Combining a CTSA and PBRN to train and engage basic scientists with community-based clincians and patients creates scientifically meaningful community–academic partnerships that accelerate translational science to implement discoveries and improve human health.
Speakers: Ana Beatriz Emiliano, MD, Berrie Diabetes Center, Columbia University Medical Center; Rabih Nemr, MD, FACS, Columbia University Medical Center; NYU Langone Brooklyn; Rhonda G. Kost, MD, Rockefeller University; Jonathan N. Tobin, PhD, Rockefeller University
Trends in Genomic Analysis: Science, Technology, Translation and Policy
Recording: Examines current and emerging genomic sequencing and other genomic analysis approaches and programs, exploring the scientific, regulatory, and policy opportunities and gaps to be addressed in this area of precision medicine.
Speakers: Teri Manolio, MD, PhD, National Institue for Human Genome Research, NIH; Greg Feero, MD, PhD, Geisel School of Medicine at Dartmouth; Matthew R. Nelson, GSK; John W. Belmonth, MD, PhD, Clinical Genomics Group, Illumina Inc.; Zivana Tezak, PhD, Center for Devices and Radiological Heath, FDA
Moderator: Scott Steele, PhD, University of Rochester Medical Center
Predictive Modeling and AI in Healthcare: What to Do with Garbage
Recording: Data from the electronic health record (EHR) are frequently used to generate predictive models, or as the basis of artificial intelligence tools, to support medical decision making and health care operations. There are fundamental limitations based on the quality of the underlying data. Missingness and errors are unlikely to be random, and shouldn’t be ignored. This is true both for developing the models and then for using these tools to make decisions at the individual patient level. In this session, recorded at Translational Science 2019, the presenter covers the principal challenges, how errors propagate through modeling processes, and how they translate to sub-optimal decision making. Potential solutions and opportunities for research are discussed.
Speaker: Jareen Meinzen-Derr, Cincinnati Children’s Hospital Medical Center
Webinar: Mount Sinai Health Hackathon: A Model of Experiential Team Science
When: November 21, 2019
Presenter: Janice Gabrilove, MD, FASP and Layla Fattah, MPharm, MEd
Launched in 2016 and now in it’s fourth year, the Mount Sinai Health Hackathon offers an innovative and novel model for team science education and entrepreneurship. Borrowing this format from the technology world, the Health Hackathon brings together individuals to form interdisciplinary teams with the aim of creating an innovative technology to solve a current problem in medical science or healthcare. This forum taps into the notion of “citizen science” and integrates diverse capabilities and domain expertise of front-line clinical providers, with insight into clinical phenotypes and care delivery challenges, with individuals reflective of wide-range of disciplines including basic science, engineering, programming, product design and business.
From an organizers perspective, the Health Hackathon aims to bring participants together in transdisciplinary teams around a shared problem, fostering experiential learning through communication, collaboration and problem-solving. It aims to cultivate an environment for participants to develop the skills and knowledge for creating technology that addresses the needs and unique challenges of the healthcare environment, and to promote healthcare innovation and an entrepreneurial ecosystem at Mount Sinai and beyond. In this webinar session, we aim to provide you with an overview of the Mount Sinai Health Hackathon experience by showcasing the vision, mission, outcomes and impact of this novel initiative. We will describe the planning involved to create a highly successful Health Hackathon, the content and format of the event, as well as outcome measures and evaluation tools we have utilized to measure the impact on team science. Our goal is to provide a new way to think about fostering team science, provide you with Health Hackathon best practices to consider, and inspire you to develop similar models of fostering team science education while promoting entrepreneurship.