|12:00 PM - 1:00 PM
- Workshop: Diversity and Inclusion in Translational Science: Success Stories and Lessons Learned
Presenters: Xinzhi Zhang, Erica Rosemond, PhD, Ewan Cobran, Anandi Krishnan, Jennifer Erves, Juan Vasquez, Joan Nagel, and Mercedes Rubio
NIH depends upon a pool of highly talented scientists from diverse backgrounds as a way to ensure a robust scientific workforce in the biomedical, clinical, behavioral and social sciences. The Clinical and Translational Science Awards (CTSA) Program supports diversity and re-entry research supplement opportunities to promote diversity and inclusion in health-related research and re-entry into biomedical and behavioral research careers. The goal of these supplements is to build a diverse clinical and translational research workforce that is prepared to improve the quality, safety, efficiency, and speed of clinical and translational science research nationally. In this session, we will highlight outstanding diversity and re-entry research supplement awardees who have used this opportunity to advance their research careers and improve public health for all. Success stories and lessons learned will be shared for an interactive discussion with attendees.
- Panel Discussion: Scaling Up Efforts to Establish and Support Numerous Community-Academic Research Teams Concurrently for Both Investigator-Initiated and Community-Driven Research
Presenters: Laurie Hassell, BS, Allison Cole, MD, MPH, and Linda Ko, PhD
Community engagement is increasingly recognized as a critical element of translational research to ensure the quality and relevance of clinical and translational studies, improve implementation of health discoveries, and improve health outcomes. However, successful engagement requires establishing relationships with community partners, training for both investigators and community partners to support effective collaboration, and engagement of multiple stakeholders. This type of community engagement is time consuming, and requires significant investigator expertise and research readiness from communities. This session will describe a community-academic connections program (henceforth Connections Program) at the Institute of Translational Health Sciences, which enables investigators to quickly engage multiple community stakeholders and embeds training, technical support and evaluation throughout the project lifespan. The Connections Program can be scaled up to support numerous research studies without overburdening the CTSA-based coordinating center or community engagement program.
- Panel Discussion: Developing Maturity Models for Translational Science Communities: Research Informatics and Learning Health Systems
Presenters: Boyd Knosp, MS, Peter Embi, Adam Wilcox, PhD, Jodyn Platt, PhD, MPH, Nicholas Anderson, and William Barnett
Academic Health Systems associated with the CTSA consortia face continuous internal and network-level change management requirements, particularly in the health IT and research informatics investments which support translational science, learning health care system activities, and responsive national initiatives.
This panel will describe the use of tools for organizational improvement called maturity models, which assess and guide planning using a sequence of discrete levels of formality and optimization for a class of processes and capabilities in one or more business domains. Join this session as the panel discusses current efforts and potential applications of maturity model frameworks to monitor dynamic improvement processes at the heart of translational research and learning health systems.
- Panel Discussion: Strategies to increase diversity in early stage product development and small businesses
Presenter: Kathleen Rousche
The value of ethnic and gender diversity has been recognized across all sectors of the American economy. A diversity of talent across the entire research enterprise is needed in order to maintain America’s position as the global leader in scientific discovery and innovation. Expanding the engagement of researchers and entrepreneurs from disadvantaged populations in early stage technology development activities will hopefully lead to new and innovative solutions to improve health equity and reduce health disparities.
This session will bring together federal and non-federal stakeholders to discuss strategies to enhance diversity in academic innovators and the biomedical workforce. Attend this session to learn how the NIH is working to understand barriers of entry to, and improve diversity in, proof of concept and small business programs.
|12:00 PM - 1:00 PM
- Capitol Hill Advocacy Panel
Join established and young investigators for a one-hour panel discussion on the contemporary policy and funding issues impacting the community, and learn how to work with advocates from your state to connect with the offices of your senators and representatives to advance the community’s legislative agenda. Registration for this session ends on Friday, March 12.
- Federal Drug Administration (FDA) Virtual Panel
Join panelists from the Food and Drug Administation for an overview of the Center for Tobacco Products Cigarettes, Enforcement Priorities for Electronic Nicotine Delivery System (ENDS), and American Indians/Alaska Natives (AI/AN) Tobacco Prevention Campaigns.
- National Institute of Health (NIH) Clinical Center Virtual Tour
Take a virtual tour of the National Institute of Health (NIH) and hear from John Gallin, MD, Chief Scientific Officer (CSO) and the Scientific Director (SD) of the NIH Clinical Center.
- Scholars Networking Session with Federal Training Partners
Join this session and hear from representatives from key federal agencies, such as the AHRQ, FDA, NIH, PCORI, and VA. Ask questions about your research and career goals and gain immediate feedback and advice.
|1:00 - 1:15 PM
|1:15 - 2:15 PM
- Panel Discussion: Training, Acquisition of Know-How and Mentorship in Clinical and Translational Research for Faculty Members/Clinicians in the Health Professions, During the COVID -19 Pandemia and Other Natural Disasters
Presenters: Margarita Irizarry-Ramirez, PhD, Ruben Garcia, PhD, Brenda Soto, Luis A. Rosario Arroyo, EdD, Nancy Davila Ortiz, Lizbelle De Jesus-Ojeda, MA,EdD, and Juan Soto Santiago, EdD
Join a panel that will introduce a supportive model to train Health Professionals /clinicians and others in Clinical and Translational Research (CTR), providing evidence of activities that work. Training in CTR for early and mid-career faculty and tenured faculty in decision making positions advances the support for CTR and provides new alternatives to develop their academic careers. Four former trainees will present their specific development benchmarks. The session will highlight the agility of the model to evolve and to attend to trainees’ needs during 2020, a year in which there were earthquakes and challenges posed by the COVID19 pandemic.
- Panel Discussion: Growing a Diverse Team Through Training Opportunities and Community Partnerships to Increase Diversity in Research Participation
Presenters: Gina Claxton, Elmer Sanders, BS, Sarah Wiehe, MD, MPH, Brownsyne Tucker Edmonds, MD, MPH, MS, Sylk Sotto, EdD, Christine Drury, Mathew Allen, PhD, Emily Hardwick, MPH, and Brenda Hudson, MA
This panel discussion will highlight the Indiana Clinical and Translational Sciences Institute (CTSI)’s established, evolving, and expanding initiatives to promote diversity and inclusion throughout the research continuum. Dive into how the Indiana CTSI develops a diverse workforce—from a pipeline model for early and continual growth of diversity and key focuses on retention among underrepresented faculty, to turning to community partners. Learn how these have translated to increased engagement of underrepresented groups in recruitment efforts, with continued attention to and respect of the community’s voice and priorities.
- Panel Discussion: Progress, Challenges and Opportunities Toward Implementation of AI and Data Science in Medicine
Presenters: Sean Mooney, PhD, Nigam Shah, MBBS, PhD, and Eneida Mendonca
Electronic Health Record (EHR) systems are sophisticated enough now to capture all aspects of clinical patient care and continue to improve. Over the time they have been in place, healthcare delivery systems have accumulated significant and increasingly useful data about patient encounters, business processes and financial operations. Data are now standardized using increasingly sophisticated and interoperable terminologies and information models (such as FHIR), enabling method development with ease. These data and methods show great promise for enabling the Learning Health System through predictive and prescriptive analytics guided by artificial intelligence to improve healthcare.
In this panel discussion, we will focus on the issues spanning the delivery science of machine learning into the clinical workflow. We will discuss our experiences and highlight foci of interest to the clinical and translational research community. Panelists will present short talks and then participate in audience discussion. We will describe investments in operational data science and what our expected outcomes are.
- Panel Discussion: Innovation to Impact - Early-stage Translational Research Programs in Academia
Presenters: Brad Martin, PhD, Molly Wasko, PhD, Aditi Martin, and Alisha R. Goldberg, MS
Join our panel discussion on establishing Innovation and Translational Research programs within academia. Since being established in 2013, Fast Forward Medical Innovation at the University of Michigan Medical School has provided groundbreaking funding programs, dynamic educational offerings, and deep industry connections to help biomedical researchers navigate the road to successful innovation and commercialization, with the ultimate goal of positively impacting human health. We do not seek to change our research faculty into entrepreneurs, but rather provide them with the tools, knowledge, funding and vocabulary to successfully interact with those that can bring their technology to market. This session will provided shared best-practices, challenges, key program topics, and network for future support.
- Panel Discussion: Digital Health: Disruption Without Being Disrupted
Presenter: Simon Lin, Yungui Huang, Chris Jensen, Burr Zimmerman, and Tyler Lieser
Join a panel researchers, entrepreneurs, and intrapreneurs as they discuss the challenges of innovation at established academic medical centers—it requires the practice of team science to engineer the desired “disruption without being disrupted”. Nationwide Children's Hospital, an affiliated partner with the CCTS of Ohio State University, experimented with jumpstarting digital health innovation through hosting special annual innovation events. Attend this session to learn of their key findings.
- Panel Discussion: Decentralized Clinical Trials: Using a Participant-Centric Approach to Transform Study Design
Presenters: Cheryl Byers, MHA, CIP, CHRC, Adit Ginde, MD, Matty Culbreth-Notaro, BSN, RN, Nichelle Cobb, PhD
COVID-19 has accelerated the adoption of technology and the re-tooling of how clinical research is conducted. One such adaptation has been to focus efforts in the exploration of de-centralized trials. De-centralized trials involves the use of technology to apply the more traditional study framework in an electronic manner. Whether you are embarking on electronic consenting, virtual or remote study visits, remote data collection or patient recruitment, engagement & retention, de-centralized trials can enable researchers access to under-represented populations and ensure compliance with trial requirements allowing for more useful data. This session will explore how a de-centralized approach to your study design will enhance participant engagement, retention and compliance. We will also explore the implications for human subjects and Institutional Review Boards who review/approve de-centralized trials.
|2:15 - 2:45 PM
|2:45 - 3:45 PM
- COVID as a Window into Health Equity: Vaccination rates and mortality rates both vary enormously by race and ethnicity. How should we as a society address this?
- Microbiome: A new era of knowledge and therapeutics
- Inflammation: A key predictor across multiple conditions, inflammation is multifactorial
- Immunotherapy: Helping more cancer patients recognize tumors and retake their bodies.
- Epigenetics & Aging: As our understanding of aging processes advances, so do our options for maximizing healthy aging.
- Decentralized Clinical Trials: Increasingly, trials are run remotely. What are tips, tricks, and tools for effective decentralization?
- COVID and Patient Permissions: At many institutions, families are restricted or denied access to patients while nurses, chaplains, and physicians may be overwhelmed. What are best practices for patient care in these times?
|3:45 - 4:00 PM
|4:00 PM - 5:15 PM
- Speed Mentoring Session: Part 1
Speed mentoring allows mentees to connect with five senior scientists over the course of an hour for mini-discussions. Speed mentoring is a great way to expand your network, ask pointed questions, get advice about finding resources, seek candid feedback, and chat informally about life in research with people who know the ropes. This session is only open to pre-registered attendees.
|4:00 - 5:00 PM
||Poster Platform Presentation
|4:00 - 5:00 PM
- Panel Discussion: Collaborative Conversations: Tackling Urgent Clinical Research Workforce Development Issues for Learning Health Systems
Presenters: Carolynn Thomas Jones, DNP, MSPH, BSN, Robert Kolb, RN, MS, Arti Shah, MPH, CHES, Karen Carter, BA, and Aric Lane, MPA
There is a critical need to grow and sustain a knowledgeable and experienced clinical research professional workforce to support the academic clinical research enterprise. In addition to expanding training and education, organizational issues should be considered for the development of best practices for recruiting, training, retaining, and sustaining the workforce, in addition to addressing gaps in the existing pipeline of future clinical research professionals.
A collaboration between University of Florida, Ohio State University and University of Washington CTSA hubs developed an initiative organized as “Collaborative Conversations- the Critical Need for Professional Workforce Development at Academic Medical Centers” became, due to COVID-19 a series of Zoom “Un-Meeting” webinars to focus on key clinical research professional workforce issues impacting the success of academic medical centers. Join this session to see shared data from the initial pre-conference needs assessment, as well as summary outputs from the individual webinars and post-meeting evaluations.
- Panel Discussion: CTSA Community Reviewer Training Program: Increasing Diverse Perspectives in Pilot Grant Reviews by Integrating Community Input
Presenters: Aileen Orlino Dinkjian, EdD, Nia Indelicato, April Bagaporo, MBA, Pamela Dillon, Jamilo Gurhan, Tanya Mathew, BDS, MS, and Megan Gutierrez, MPH
Learn about the NIH-supported Community Reviewer Training Program from the University of Arkansas for Medical Sciences, University of Southern California, University of California, Irvine, Ohio State University, and Virginia Commonwealth University. Community members have been trained to review CTSA pilot grant applications (based on the UAMS training model) and have participated in actual pilot grant reviews and study section meetings.
Attend to learn more about the immediate goal of this project: to implement and assess across multiple CTSA hubs a scalable mechanism, allowing diverse representatives of communities affected by a disease or condition to meaningfully participate in review of pilot grant research proposals. Our long term goal is to enhance the review process across the CTSA consortium and other funding agencies, by systematic integration of a multi-faceted community perspective.
- Panel Discussion: Learning Healthcare: Empowering Embedded, Pragmatic RCTs
Presenter: Cheryl Gatto, PhD, Chris Lindsell, PhD, Coby Stone, MD, MPH, Robert Freundlich, MD, MS, MSCI, Autumn Zuckerman, PharmaD, BCPS, AAHIVO, CSP, Edward Qian, MD, and Matthew Semler, MD, MSCI
In recent years, various healthcare entities have implemented more formalized structure to promote aspiration and evolution toward becoming exemplar Learning Healthcare Systems (LHS). With a focus on “Learning from what we do, and then doing what we learn”, an LHS strives to ingrain a cycle of continuous discovery and implementation within the context of routine care delivery and hospital operations. To this end, our institution specifically targets the identification, development, and support of embedded, pragmatic, randomized controlled trial opportunities with a unique research infrastructure installation. During this session, we will detail the “LHS Platform”. We will touch on how our program leverages a translational, transdisciplinary, team science approach with strengths in clinical trial design and conduct, biostatistics, regulatory affairs, project management, data science and informatics, and community engagement. This organization enables unparalleled collaboration between clinical research and clinical operations, yielding a productive study pipeline and broad portfolio active within diverse specialty areas. We will highlight our methods and provide concrete examples of the Platform’s functionality.
- Panel Discussion: Opportunities for Translating Workforce Development Strategies Across the Consortia Before, During, and After a Pandemic
Presenters: Alicia Hoke, MP, CHES, Jody McCullough, AA, Laura Hanson, MS, PMP, Whitney Bondurant, JD, DHA, Leslie Musshafen, MBA, CRA, CPRA, Jennifer Kraschnewski, MD, MPH, and Jennifer Weis, MAN
This panel session will provide an overview and discussion of the effort to determine the portability of an existing workforce development program for clinical research staff established at Mayo Clinic, and its implementation at Penn State University and University of Mississippi Medical Center as part an effort funded through a CTSA supplement grant. Panel members will discuss the principles of a robust clinical research workforce development program, key considerations for implementation at the partnering institutions, audiences served, and the portability of the program infrastructure to additional CTSA hubs. In addition, the panel will highlight the collaborative effort to pivot workforce development activities to virtual platforms in response to the COVID-19 pandemic. Participants will engage in discussion of applications of these experiences in their own settings.
- Non-CME Panel Discussion: CR Forum Industry Roundtable Part 1: Engagement of Industry in Clinical Research
Presenters: Anantha Shekhar and Andrea Van Hook, BA
The Industry Roundtable brings together researchers from academic medical health centers, industry partners, and advocacy organizations to discuss and advance non-proprietary issues relating to drug and device development, evaluative and comparative effectiveness research, and the dissemination of knowledge about clinical research findings. In this session, industry representatives and academic health center researchers will present best practices and commentary on developing diverse and collaborative teams and forging industry/academic research partnerships.