|11:15 - 11:45 AM
||ACTS Business Meeting
|12:00 - 1:00 PM
||ACTS Ambassadors Introduction
- A.) Introduction to program
- B.) Introduction to translational science
- C.) Introduction to ACTS
|12:00 - 1:00 PM
- Panel Discussion: Amplifying the CTSA Impact: Workforce Development Strategies Beyond the Consortium
Presenters: Brenda Eakin, MS, Karen Weavers, M.Ed., Vidya Iyer, MD, CPI, Enid Garcia-Rivera, MD, MPH, Robert Sege, MD, PhD, and Elias Samuels, PhD
Promoting effective research requires CTSA hubs to engage in novel workforce development initiatives that extend beyond the Consortium. Given the scope of the future workforce and the need to move health research from bench to bedside, no single hub can contribute to this mission in isolation. Recent efforts to ensure reliability and replicability of data show how important it is for institutions to form collaborations that promote access to training resources and best practices developed by CTSAs.
Join representatives from the University of Michigan, the Mayo Clinic, and Tufts CTSI as they describe and discuss successful collaborations between institutions.
- Panel Discussion: CR Forum: Broadly Engaged Team Science: Building Trust With Diverse Groups
Presenters: Andrea Van Hook, BA, Harry Selker, MD, MSPH, and Pamela Davis, MD,
More information to come.
- Panel Discussion: The Role of Translational Science Enterprises in Advancing the Learning Health System
The focus of this panel is on building trust in the community through reflecting, supporting and promoting diversity in our workforce and research partnerships.
- Panel Discussion: Prepped for Success: Initiating Collaborations with Statisticians Pre- and Post- COVID
Presenters: Leah Welty, PhD, Jareen Meinzen-Derr, PhD, MPH, Robert Oster, PhD, Lori Lyn Price, MAS, MLA, Jodi Lapidus, PhD, and Ann Brearley, PhD
For new investigators, initiating a collaboration with a statistician may seem a bit uncomfortable, even scary, due to not knowing what to expect. Post-COVID, it may be even harder to know what to expect. However, the COVID pandemic has forced us to make adaptations that, in some ways, have made collaborations with statisticians easier, with the ability to access expertise not only locally but also nationally (and even globally). Regardless of whether the meeting takes place in-person or remotely, a successful and productive collaboration can be built upon a successful first meeting, which includes discussing and clearly defining both the goals of the study and how the statistician and the investigator will work together to achieve those goals. This panel discussion will provide tips for a successful first meeting and for further collaboration, as well as set forth the roles and responsibilities for both the researcher and the statistician.
- Panel Discussion: Accelerating Large-Scale Research: Methods for Creative Brainstorming and Strategic Action Planning
Presenters: Elizabeth LaPensee, PhD and Aalap Doshi, MS
Interdisciplinary collaboration is widely considered essential to addressing complex scientific and societal problems. Funding agencies are increasingly seeking team-based approaches to tackling research questions, and the Michigan Institute for Clinical & Health Research at the University of Michigan responded by deploying an initiative that encourages and supports the development of large-scale grants (e.g. NIH U- and P-series mechanisms). Attend this session to learn how to leverage various aspects of design thinking and strategic action planning intended to drive teams through stages of ideation all the way to group consensus around opportunities to pursue, including realistic next steps. We will discuss our aim to foster new methods of team thinking and doing that allow collaborative networks to create a shared research vision; to commit reasonable time and resources to advancing the research and partnerships; and to ultimately develop compelling large-scale grant applications to fund their big ideas and synergistic efforts.
|12:00 - 1:15 PM
- Speed Mentoring Session: Part 2
Speed mentoring allows mentees to connect with five senior scientists over the course of an hour for mini-discussions. Speed mentoring is a great way to expand your network, ask pointed questions, get advice about finding resources, seek candid feedback, and chat informally about life in research with people who know the ropes.
|1:00 - 1:15 PM
|1:15 - 2:15 PM
- Panel Discussion: A Novel Online Course in Translational Science Offered by NCATS: Course Design, Content, and Evaluation Results
Presenters: Jessica Faupel-Badger, PhD, MPH, Amanda Vogel, PhD, MPH, and Shadab Hussain, PhD
The NCATS Education Branch is creating new education opportunities aimed at advancing understanding of translational science principles.In this panel, we highlight use of the case study method as an approach for teaching these emerging concepts and detail our first online translational science course, piloted in 2020 and open to the scientific community.The course teaches key principles of translational science including novelty, process innovation and efficiency, acceleration of timelines, and boundary-crossing partnerships, and highlights how these principles have been operationalized in a real-world project. The specific case examined the development of a compound to treat advanced metastatic cancer that is now in phase 1 clinical trials. The course was evaluated through pre- and post-course student surveys (n=100) and analyses showed significant improvements in translational science knowledge and alignment towards team science attitudes in translational research. Additional course outcomes and future directions for translational science education will be discussed.
- Workshop: Engaging Clinical Trial Participants through Effective Conversations
Presenters: Brian Sostek, BA and Megan Larson
A well run informed consent process, whether done in person or online, can positively affect participant recruitment, retention, engagement, honesty, consistency, and accuracy. It can also ensure their complete and thorough understanding of the trial itself and their role in it. While efficiency in the consent process is always a concern in the short term, in the long run, it’s always worth investing the time and energy with your participants to establish rapport in the true sense of the word: a close and harmonious relationship, in which the people concerned understand each other's feelings or ideas and communicate well.
In this workshop, NarrativePros leads an energizing, enjoyable and--most importantly--applicable dive into their tried and true techniques for having productive conversations that establish the kind of engagement, trust, and commitment every researcher wants from their participants. Through lecture and interactive exercises, we’ll apply improvisation techniques, intentional listening skills, and perspective shifting approaches to show you how to end up with truly informed participants.
- Panel Discussion: Making Dissemination and Implementation Research Ubiquitous in Translational Science
Presenters: Kathleen Stevens, RN, EdD, FAAN, Jonathan Tobin, PhD, Aaron Leppin, MD, Jane E. Mahoney, MD, and Andrew Quanbeck, PhD
Health sciences seek to turn research knowledge into practice and benefit; this session raises awareness of the potential of Dissemination and Implementation (D&I) Sciences for improving population health. D&I sciences evolved rapidly in the past decade and have experienced a recent surge. Developments are occurring in theories, frameworks, methods, study design, analytics, standards of rigor, and application to problems.
This session focuses on these emerging fields, examining D&I sciences across the entire translational science spectrum. It explores state of D&I sciences, benefits of D&I in every stage of translation, and expansion of D&I capacity through workforce development.
Led by members from the NCATS Dissemination & Implementation (D&I) Research Working Group, the session encourages participants to increase impact of their research using D&I approaches that build bridges, span barriers, and link evidence to practice and impact. Rapid fire topics offer an overview, drill down on each stage of translational science, address scientific workforce capacity and team science, and envision the future of D&I applied to translational research. Discussions operationalize concepts through examples, including COVID-19, journal articles, and resources for further depth.
- Panel Discussion: Dimension Reduction and Feature Selection Methods: Reducing the Complexity
Presenters: Lauren Balmert, PhD and Erika Helgeson, PhD
Methods for reducing dimensionality and identifying important variables among a large number of predictors have become increasingly important in the areas of omics, health, and behavioral and social science research. The evolution of these statistical methods has impacted how we analyze data and interpret findings.
This session will provide an introduction to statistical and machine learning methods for dimension reduction, variable selection, and classification methods. Emphasis will be placed on the types of research questions that can be answered, advantages over traditional methods, and interpretation of results. Primary topics will include: principal components analysis, orthogonal partial least squares, discriminant analysis, lasso regression, and random forests. Presenters will illustrate these methodologies with real data applications.
- Panel Discussion: CCTS: Health Policy in the New Administration
Presenter: William Lowe, MD, Dale Dirks, and Dane Christianses, MBA
This session will feature senior staff from the Senate and House committees responsible for clinical and translational research funding. They will discuss the Biden Administration’s health policy priorities and how the Senate and the House are likely to respond.
|2:15 - 3:00 PM
||ACTS Ambassadors Q/A Session
- A.) Education with TL1 scholar mentor
- B.) Interaction with panelists/presenters from previous ACTS session
|2:15 - 2:45 PM
|2:45 - 3:45 PM
|3:45 - 4:00 PM
|4:00 - 5:00 PM
- Scholar Career Pathways
This event, designed for students, fellows and early career attendees, will feature the opportunity to talk one on one in a relaxed reception-like atmosphere with experts from diverse fields of translational science.
- Help! I'm Mid-Career and Stuck
This session is for anyone who is mid career and either has less mentorship than they want or who has faced career challenges. Here a group of six experienced tenured faculty will define the problem, share their experiences and answer questions from the audience.
|4:00 - 5:00 PM
- Panel Discussion: Community-Academic Partnerships to Train Community Health Workers and Promotoras in Research
Presenters: Susan Murphy, ScD, OTR, Gustavo Loera, and Irvin (PeDro) Cohen, Ed.D.
Regardless of whether they have formal roles on study teams or informal roles of supporting research in communities where they work, community health workers and promotoras (CHW/Ps) are vital in the implementation of rigorous research in communities. The importance of the role of CHW/Ps has increased during the COVID-19 pandemic where they help to foster trust in communities to support health and research efforts. This session will describe an NIH-funded project from three CTSA-funded institutions in which the goal is to develop, demonstrate and disseminate competency-based research training for CHW/Ps. A community-academic partnership model will be described as a main method of training using peer Champions as the trainers in communities. A planned, broadly accessible toolbox of resources including culturally- and linguistically-appropriate materials will be discussed. Community partners from the universities associated with this project will discuss how training can be applied in their specific settings and potential adaptations to training in the field. Lastly, the planned dissemination of the training and toolbox using a newly-established network of community advisory boards at universities around the nation will be highlighted.
- Lecture: Linking Dissemination and Implementation Science to Learning Health Systemss
Presenters: Paul Meissner, MSPH, BS, Nancy (Nana) Bennett, MD, MS, and Elissa Orlando, MPA
Learning Health Systems (LHS) iteratively implement and evaluate health improvement projects. Dissemination and implementation (D&I) science is the study of evidence-based practices in real-world settings, a critical tool for LHS. This presentation explores intersections between LHS and D&I science in Clinical and Translational Science Awards (CTSAs) institutions and identifies critical components of collaboration.
- Panel Discussion: Approaches to Data Discovery: Connecting Researchers Through Data
Presenters: Nicole Contaxis, MLIS, Kristi Holmes, PhD, Alisa Surkis, PhD, MLS, Sara Gonzales, MLIS Terrie Wheeler, and Peter Oxley
Across the CTSA consortium a number of approaches have been taken towards facilitating the formation of translational research teams. This panel focuses on data discovery as an approach towards connecting researchers through data, as well as empowering those researchers to share and locate data for re-use. NYU Langone Health, Weill Cornell Medicine, and Northwestern University have taken different approaches to improving data discovery at their institutions, and are members of the Data Discovery Collaboration (DDC), a cross-institutional, platform-agnostic collaboration with the aim of enhancing the discovery of data in order to maximize its value. The objective of this panel is to present the approaches, successes, and challenges of each institution, and to discuss how the DDC enhances each of these institutional efforts. The panelists will also discuss the structure of and requirements for joining the DDC, innovations that will be made possible by this collaboration, and thoughts on upcoming challenges.
- Panel Discussion: CR Forum Industry Roundtable Part 2: Engagement of Industry in Clinical Research
Presenter: Anantha Shekhar, MD, PhD and Andrea Van Hook, BA
The Industry Roundtable brings together researchers from academic medical health centers, industry partners, and advocacy organizations to discuss and advance non-proprietary issues relating to drug and device development, evaluative and comparative effectiveness research, and the dissemination of knowledge about clinical research findings. In this session, industry representatives and academic health center researchers will present best practices and commentary on developing diverse and collaborative teams and forging industry/academic research partnerships.